Work Package 4
WP4: Evaluation and validation of an in vivo imaging technique for measuring brain tumour magnitude -- Leader: TEIA (M1-M36)
WP4 includes the tasks that aim to: test several labelling techniques
in order to develop a standardised (high radiolabeling yield,
radiochemical purity and radiochemical, in vitro and in vivo stability)
method for labeling adequately preformed micro/nanoparticles with
gamma-emitting radionuclides; carry out biodistribution studies in
normal and brain tumor models in order qyantify quantify the uptake of
labelled micro/nanoparticles in various healthy organs or/and tissues
and the pathological site; perform in vivo dynamic scintigraphic and
tomographic SPECT studies in small mice; quantification of imaging
results; design and optimize of imaging protocols for planar dynamic
and tomographic SPECT studies.
